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Proper time of applying generic Retin-A  (Japanese : トレチノイン ) cream or gel is at night. You should take a small amount of this medicine and apply it in a thin layer on your affected skin. A little amount is more than sufficient to give you long-term results.

Wash your face in the daybreak using a soft facial scrub or an unsmooth wash cloth. This will serve to cut down the visible peeling. Once you wash your face, the next task is to use a sound water-based moisturizer for making your skin less dry. Even men can apply moisturizer on their skin too. The moisturizer will negate the drying issue of generic Retin-A to make it more endurable.